Ambient Air Pollution And Pregnancy Outcomes: A Review Of The Literature

Over the last decade or so, a large number of studies have investigated the possible adverse effects of ambient air pollution on birth outcomes. We reviewed these studies, which were identified by a systematic search of the main scientific databases. Virtually all reviewed studies were population based, with information on exposure to air pollution derived from routine monitoring sources. Overall, there is evidence implicating air pollution in adverse effects on different birth outcomes, but the strength of the evidence differs between outcomes. The evidence is sufficient to infer a causal relationship between particulate air pollution and respiratory deaths in the postneonatal period. For air pollution and birth weight the evidence suggests causality, but further studies are needed to confirm an effect and its size and to clarify the most vulnerable period of pregnancy and the role of different pollutants. For preterm births and intrauterine growth retardation (IUGR) the evidence as yet is insufficient to infer causality, but the available evidence justifies further studies. Molecular epidemiologic studies suggest possible biologic mechanisms for the effect on birth weight, premature birth, and IUGR and support the view that the relation between pollution and these birth outcomes is genuine. For birth defects, the evidence base so far is insufficient to draw conclusions. In terms of exposure to specific pollutants, particulates seem the most important for infant deaths, and the effect on IUGR seems linked to polycyclic aromatic hydrocarbons, but the existing evidence does not allow precise identification of the different pollutants or the timing of exposure that can result in adverse pregnancy outcomes.

TABLE OF CONTENTS
Cover Page – – – – – – – – – –
Title Page – – – – – – – – – –
Certification – – – – – – – – – –
Dedication – – – – – – – – – –
Acknowledgement – – – – – – – – –
Abstract – – – – – – – – – –
Table of Content – – – – – – – – –
Chapter One: Introduction
Background of the Study – – – – – –
Statement of the Problem – – – – – –
Objectives of the Study – – – – – – –
Research Questions – – – – – – –
Research Hypotheses – – – – – – –
Significance of the Study – – – – – – –
Scope/ Limitation of the Study – – – – – –
Definition of Terms – – – – – – –
Chapter Two: Review of Related Literature
2.1 Introduction – – – – – – – – –
2.2 Conceptual Framework – – – – – – –
2.3 Theoretical Framework – – – – – – –
2.4 Empirical Review – – – – – – – –

Chapter Three: Research Methodology
3.1 Introduction – – – – – – – –
3.1 Research Design – – – – – – – –
3.3 Area of the Study – – – – – – – –
3.4 Population of the Study – – – – – – –
3.5 Sample Size and Sampling Techniques – – – –
3.6 Instrumentation – – – – – – – –
3.7 Validation of the Instrument – – – – – –
3.8 Administration of the Instrument – – – – –
3.9 Method of Data Analysis – – – – – – –

Chapter Four: Presentation, Analysis and Interpretation of Data
4.1 Introduction – – – – – – – – –
4.2 Presentation and Analysis of Data – – – – –
4.3 Testing of Hypotheses – – – – – – –
4.4 Discussion of Findings – – – – – – –
Chapter Five: Summary, Conclusion and Recommendations
5.1 Introduction – – – – – – – – –
5.2 Summary – – – – – – – – –
5.3 Conclusion – – – – – – – – –

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