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HISTOLOGICAL STUDY OF ENDOMETRIAL BIOPSIES IN JOS UNIVERSITY TEACHING HOSPITAL (A FIVE YEAR RETROSPECTIVE STUDY 1ST JANUARY 1998 – 31ST DECEMBER 2002)
Abstract
Background: Endometial biopsies constitute one of the frequently sampled tissues in
gynaecological practice. This study aims at giving an insight into the pattern of
endometrial pathology at Jos University Teaching Hospital.
Methods: All slides from endometrial biopsies over a period of five years were retrieved
and re-evaluated for confirmation of diagnosis. Clinical data were obtained from
histopathology request forms.
Results: A review of endometrial biopsies slides from 556 patients revealed that
pregnancy related diagnosis was the commonest, representing 302 (54.3%) of
histopathological diagnosis, followed by endometrial hyperplasia. Hydatidiform mole,
which ranked third, constituted 58 (10.4%) of the cases studied. Choriocarcinoma was
the leading malignancy representing 10 (45%) of the malignant tumours and 10 (1.8%) of
all the endometrial biopsies. Endometrial adenocarcinoma, stromal sarcoma and
metastatic cancer constituted 6 (1.0%), 3 (0.5%) and 3 (0.5%) respectively of the cases.
Conclusion: The commonest endometrial pathology seen in JUTH over the study period
was products of conception which peak in the third decade of life; primary malignancies
of the endometrium are uncommon in JUTH and they represent just about 2%.
