A TEN YEAR HISTOPATHOLOGICAL REVIEW OF CERVICAL NEOPLASMS IN LAGOS UNIVERSITY TEACHING HOSPITAL, IDI-ARABA, LAGOS, NIGERIA (1993– 2002): A RETROSPECTIVE STUDY

  • : Ms Word, Ms Word Format
  • : 82 Pages
  • : ₦3000
  • : 1-5 Chapters
  •  
  • Click to DOWNLOAD Materials

A TEN YEAR HISTOPATHOLOGICAL REVIEW OF CERVICAL NEOPLASMS IN LAGOS UNIVERSITY TEACHING HOSPITAL, IDI-ARABA, LAGOS, NIGERIA (1993– 2002): A RETROSPECTIVE STUDY

Abstract

This work is a retrospective study of the histopathological pattern of cervical
neoplasia carried out in the Department of Morbid Anatomy of Lagos University Teaching Hospital between January 1993 and December 2002.
All cases with diagnosis of various forms of cervical neoplasia were reviewed
from the records of the department. The corresponding slides were retrieved
and where necessary the paraffin blocks were recut and restained and Alcian
blue was used as a special stain where necessary. The tumours were
classified according to WHO.5
A total of 806 cervical biopsies were received of which 542 (67.2%) were true
cervical neoplasia. Malignant lesions were commoner than their benign
counterpart and accounted for 410 (75.6%) of cases. Squamous cell
carcinoma was the predominant type and constituted 88.0% of malignant
lesions. The non-keratinizing type was the predominant variant and
constituted 67.3% of the squamous cell carcinoma. The mean age for
carcinoma was 54.8 years. CIN the premalignant lesion for squamous cell
carcinoma accounted for only 47 cases (8.7%) with a mean age of 37.5 years
approximately 17 years before the invasive form. Adenocarcinoma accounted
for 4.9% of all malignancies and there were only 2 cases (0.4%) of sarcoma
seen and both were leiomyosarcoma.
Benign lesions accounted for 132(24.4%) of cervical neoplasia with
endocervical polyps as the most common followed by leiomyoma.
This study suggests that cervical neoplasia are common cervical lesions in this
environ and that the malignant variants are commoner than their benign
counterpart with squamous cell carcinoma being the most predominant type
of cervical neoplasia. The age incidence as well as the histological
characteristics appear similar to what is observed in previous studies from Nigeria and other parts of the world.

A TEN YEAR HISTOPATHOLOGICAL REVIEW OF CERVICAL NEOPLASMS IN LAGOS UNIVERSITY TEACHING HOSPITAL, IDI-ARABA, LAGOS, NIGERIA (1993– 2002): A RETROSPECTIVE STUDY

Sharing is caring!

Leave a Reply