HISTOPATHOLOGICAL PATTERN ON THYROID NEOPLASMS SEEN IN UNIVERSITY OF ILORIN TEACHING HOSPITAL (JANUARY, 1979- DECEMBER, 2007)

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HISTOPATHOLOGICAL PATTERN ON THYROID NEOPLASMS SEEN IN UNIVERSITY OF ILORIN TEACHING HOSPITAL (JANUARY, 1979- DECEMBER, 2007)

Abstract

In this twenty –nine year (1979-2007) retrospective study, an attempt is made to determine the
histopathological patterns of the various thyroid neoplasma seen at the Pathology department of
University of Illorin Teaching Hospital, Ilorin. Kwara state Nigeria. One hundred and fifteen
histologically diagnosed thyroid neoplasms were reviewed which represented 12.8% of all
thyroidectomy specimens. These neoplasms consisted of 56 (48.7%) carcinomas. 55(47.8%)
ademomas, 3 teratomas (2.6%) and I case of Burkitt’s lymphoma (0.9%). Fifty-eight cases
(50.4%) were benign neoplasms while 57 (49.6%) cases were malignant, giving a ratio of 1:1.
Eighty-nine cases occurred in females while 26 cases were recorded in males, giving a male to
female ratio of 1:3.4
The age of patients with carcinoma ranged from 12-18 years with a medium age of 38 years. The
female to male ratio was 2.5:1 (40 females, 16 males). The common histological variants
(follicular, papillary, and anaplastic) of thyroid carcinoma occurred among the cases reviewed
with differentiated (papillary and follicular) carcinomas accounting for 92.7% of cases.
Follicular carcinoma was the most common and accounted for 67.8%, followed by papillary
carcinoma variant, which accounted for 25% with a ratio of 2.7:1. Anaplastic carcinoma and
poorly differentiated carcinoma accounted for 3.6%, and 1.8% respectively. Hurthle cell
carcinoma a variant of follicular carcinoma also accounted for 1.8%. Thyroid adenomas
occurred over an age range of 14-70 years with a median age of 37 years. The female to male
ratio was 7:1 (48 female, 7 males). All the adenomas were follicular adenoma. Three cases of
mature teratoma were recorded, in a 4-month-old female and in 11 and 35 year old males.

HISTOPATHOLOGICAL PATTERN ON THYROID NEOPLASMS SEEN IN UNIVERSITY OF ILORIN TEACHING HOSPITAL (JANUARY, 1979- DECEMBER, 2007)

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